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1

Phase I Clinical Trial of a Selective Inhibitor of CYP17, Abiraterone Acetate, Confirms That Castration-Resistant Prostate Cancer Commonly Remains Hormone Driven

Attard, G., Reid, A. H.M., Yap, T. A., Raynaud, F., Dowsett, M., Settatree, S., Barrett, M., Parker, C., Martins, V., Folkerd, E., Clark, J., Cooper, C. S., Kaye, S. B., Dearnaley, D., Lee, G., de Bon

Journal:

Journal of Clinical Oncology

Year:

2008

Language:

english

File:

PDF, 743 KB

english, 2008

2

The relationship between 17β hydroxysteroid dehydrogenase and breast tumour site and size

P. A. Beranek, E. J. Folkerd, C. J. Newton, M. J. Reed, M. W. Ghilchik, V. H. T. James

Journal:

International Journal of Cancer

Year:

1985

Language:

english

File:

PDF, 282 KB

english, 1985

3

An automated technique for the simultaneous determination of cations in nanoliter volumes

Stocking, Christopher J, Slater, Jonathan M, Unwin, Robert, Walter, Stephen, Folkerd, Elizabeth

Journal:

Kidney International

Year:

1999

Language:

english

File:

PDF, 438 KB

english, 1999

4

Metabolic syndrome and renal sodium handling in three ethnic groups living in England

A. Barbato, F. P. Cappuccio, E. J. Folkerd, P. Strazzullo, B. Sampson, D. G. Cook, K. G. M. M. Alberti

Journal:

Year:

2004

Language:

english

File:

PDF, 157 KB

english, 2004

5

Association between endogenous plasma hormone concentrations and fracture risk in men and women: the EPIC-Oxford prospective cohort study

Andrew W. Roddam, Paul Appleby, Rachel Neale, Mitch Dowsett, Elizabeth Folkerd, Sarah Tipper, Naomi E. Allen, Timothy J. Key

Journal:

Journal of Bone and Mineral Metabolism

Year:

2009

Language:

english

File:

PDF, 215 KB

english, 2009

6

A randomized trial exploring the biomarker effects of neoadjuvant sequential treatment with exemestane and anastrozole in post-menopausal women with hormone receptor-positive breast cancer

O. C. Freedman, E. Amir, W. Hanna, H. Kahn, F. O’Malley, G. Dranitsaris, D. E. C. Cole, S. Verma, E. Folkerd, M. Dowsett, M. Clemons

Journal:

Breast Cancer Research and Treatment

Year:

2010

Language:

english

File:

PDF, 257 KB

english, 2010

7

Associations of endogenous testosterone and SHBG with glycated haemoglobin in middle-aged and older men

Judith S. Brand, Nicholas J. Wareham, Mitch Dowsett, Elizabeth Folkerd, Yvonne T. van der Schouw, Robert N. Luben, Kay-Tee Khaw

Journal:

Clinical Endocrinology

Year:

2011

Language:

english

File:

PDF, 81 KB

english, 2011

8

Transepithelial electrochemical gradients in the proximal convoluted tubule during potassium depletion in the rat

D. G. Shirley, S. J. Walter, E. J. Folkerd, R. J. Unwin, M. A. Bailey

Journal:

The Journal of Physiology

Year:

1998

Language:

english

File:

PDF, 202 KB

english, 1998

9

Urinary 6-sulfatoxymelatonin levels and their correlations with lifestyle factors and steroid hormone levels

Eva S. Schernhammer, Candyce H. Kroenke, Mitch Dowsett, Elizabeth Folkerd, Susan E. Hankinson

Journal:

Journal of Pineal Research

Year:

2006

Language:

english

File:

PDF, 123 KB

english, 2006

10

Effects of the Potassium Channel Blocker Barium on Sodium and Potassium Transport in the Rat Loop of Henle In Vivo

S. J. Walter, D. G. Shirley, E. J. Folkerd, R. J. Unwin

Journal:

Experimental Physiology

Year:

2001

Language:

english

File:

PDF, 122 KB

english, 2001

11

The biology of steroid hormones and endocrine treatment of breast cancer

Mitch Dowsett, Elizabeth Folkerd, Deborah Doody, Ben Haynes

Journal:

Year:

2005

Language:

english

File:

PDF, 224 KB

english, 2005

12

P155 Anastrozole and letrozole – an investigation and comparison of quality of life, tolerability and morbidity

J.M. Dixon, E.J. Macaskill, F. McCaig, L. Renshaw, J. Murray, M. McHugh, O. Dixon, E. Folkerd, C. Langridge, L. Fallowfield

Journal:

Year:

2007

Language:

english

File:

PDF, 46 KB

english, 2007

13

FAILURE OF FSH TO INFLUENCE AROMATIZATION IN HUMAN ADIPOSE TISSUE

E. J. FOLKERD, H. S. JACOBS, Z. VAN DER SPUY, V. H. T. JAMES

Journal:

Clinical Endocrinology

Year:

1982

Language:

english

File:

PDF, 261 KB

english, 1982

14

17β-HYDROXYSTEROID DEHYDROGENASE AND AROMATASE ACTIVITY IN BREAST FAT FROM WOMEN WITH BENIGN AND MALIGNANT BREAST TUMOURS

P. A. BERANEK, E. J. FOLKERD, M. W. GHILCHIK, V. H. T. JAMES

Journal:

Clinical Endocrinology

Year:

1984

Language:

english

File:

PDF, 445 KB

english, 1984

15

A molecular size determination of Rh(D) antigen by radiation inactivation

Elizabeth J. Folkerd, J.C. Ellory, N.C. Hughes-Jones

Journal:

Immunochemistry

Year:

1977

Language:

english

File:

PDF, 234 KB

english, 1977

16

Studies of oestrogen metabolism in postmenopausal women with cancer

V.H.T. James, M.J. Reed, Elizabeth J. Folkerd

Journal:

Journal of Steroid Biochemistry

Year:

1981

Language:

english

File:

PDF, 1.19 MB

english, 1981

17

Studies on the activity of 17β-hydroxysteroid dehydrogenase in human adipose tissue

E.J. Folkerd, V.H.T. James

Journal:

Journal of Steroid Biochemistry

Year:

1982

Language:

english

File:

PDF, 371 KB

english, 1982

18

Oestrogen production in adipose tissue from normal women and women with endometrial cancer In vitro

E.J. Folkerd, M.J. Reed, V.H.T. James

Journal:

Journal of Steroid Biochemistry

Year:

1982

Language:

english

File:

PDF, 623 KB

english, 1982

19

Aromatization of steroids in peripheral tissues

E.J. Folkerd, V.H.T. James

Journal:

Journal of Steroid Biochemistry

Year:

1983

Language:

english

File:

PDF, 400 KB

english, 1983

20

The action of dexamethasone and prolactin on aromatase activity in human adipose tissue

E.J. Folkerd, V.H.T. James

Journal:

Journal of Steroid Biochemistry

Year:

1984

Language:

english

File:

PDF, 307 KB

english, 1984

21

Aromatase activity in uterine leiomyomata

E.J. Folkerd, C.J. Newton, K. Davidson, M.C. Anderson, V.H.T. James

Journal:

Journal of Steroid Biochemistry

Year:

1984

Language:

english

File:

PDF, 672 KB

english, 1984

22

Suppression of ovarian function in combination with an aromatase inhibitor as treatment for advanced breast cancer in pre-menopausal women

K.L. Cheung, A. Agrawal, E. Folkerd, M. Dowsett, J.F.R. Robertson, L. Winterbottom

Journal:

European Journal of Cancer

Year:

2010

Language:

english

File:

PDF, 263 KB

english, 2010

23

Influences on circulating oestrogens in postmenopausal women: Relationship with breast cancer

Anne Kendall, Elizabeth J. Folkerd, Mitch Dowsett

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2007

Language:

english

File:

PDF, 346 KB

english, 2007

24

The relationship between factors affecting endogenous oestradiol levels in postmenopausal women and breast cancer

Elizabeth J. Folkerd, Lesley-Ann Martin, Anne Kendall, Mitch Dowsett

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2006

Language:

english

File:

PDF, 218 KB

english, 2006

25

Testosterone, SHBG and differential white blood cell count in middle-aged and older men

Judith S. Brand, Yvonne T. van der Schouw, Mitch Dowsett, Elizabeth Folkerd, Robert N. Luben, Nicholas J. Wareham, Kay-Tee Khaw

Journal:

Year:

2012

Language:

english

File:

PDF, 202 KB

english, 2012

26

A simple method for the detection and assay of C1

Elizabeth J. Folkerd, N.C. Hughes-Jones

Journal:

Journal of Immunological Methods

Year:

1979

Language:

english

File:

PDF, 124 KB

english, 1979

27

Are Estring® and Vagifem® Equally Effective and Safe for the Treatment of Urogenital Atrophy in Breast Cancer Patients on Aromatase Inhibitor Therapy?

C.E. Simmons, I. Kuchuk, O.C. Freedman, T. Colgan, A. Dodd, K. Kulhanek, J. Sheiner, G. Dranitsaris, M. Dowsett, E. Folkerd, M.J. Clemons

Journal:

Clinical Oncology

Year:

2012

Language:

english

File:

PDF, 116 KB

english, 2012

28

159 POSTER Re-inducing sensitivity to abiraterone acetate, a novel CYP17 inhibitor with a high level of anti-tumour activity in castration resistant prostrate cancer

N. Oommen, G. Attard, A. Reid, L. Folkerd, P. Fong, J. Hunt, M. Dowsett, D. Dearnaley, C. Parker, J. De-Bono

Journal:

European Journal of Cancer Supplements

Year:

2008

Language:

english

File:

PDF, 59 KB

english, 2008

29

158 POSTER Abiraterone acetate (AA), an irreversible inhibitor of CYP17, has significant and durable anti-tumor activity in both chemotherapy- naive and docetaxel treated castration-resistant prostate cancer (CRPC)

G. Attard, A. Reid, N. Babu Oommen, L. Folkerd, D. Olmos, E. Thompson, G. Maier, M. Dowsett, D. Dearnaley, J.S. De Bono

Journal:

European Journal of Cancer Supplements

Year:

2008

Language:

english

File:

PDF, 59 KB

english, 2008

30

5027 A randomized, phase III trial exploring the effects of neoadjuvant sequential treatment with steroidal (exemestane) and non-steroidal (anastrozole) aromatase inhibitors on biomarkers in post-menopausal women with hormone receptor positive locally advanced breast cancer (LABC)

O. Freedman, E. Amir, G. Dranitsaris, M. Dowsett, D.E.C. Cole, W. Hanna, F. O'Malley, E. Folkerd, S. Verma, M.J. Clemons

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

PDF, 49 KB

english, 2009

31

Polymorphisms, endogenous hormone levels and familial breast cancer risk in premenopausal women

K Walker, O Fletcher, N Johnson, C Palles, E Folkerd, SG Hillier…

Journal:

Breast Cancer Research

Year:

2010

Language:

english

File:

PDF, 390 KB

english, 2010

32

Sex steroids, growth factors and mammographic density: a cross-sectional study of UK postmenopausal Caucasian and Afro-Caribbean women

Valerie A McCormack, Mitch Dowsett, Elizabeth Folkerd…

Journal:

Breast Cancer Research

Year:

2009

Language:

english

File:

PDF, 180 KB

english, 2009

33

Deficits in plasma oestradiol measurement in studies and management of breast cancer

Mitch Dowsett, Elizabeth Folkerd

Journal:

Breast Cancer Research

Year:

2004

Language:

english

File:

PDF, 54 KB

english, 2004

34

Changes in Estradiol and Testosterone Levels in Postmenopausal Women After Changes in Body Mass Index

Jones, Michael E., Schoemaker, Minouk, Rae, Megan, Folkerd, Elizabeth J., Dowsett, Mitch, Ashworth, Alan, Swerdlow, Anthony J.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2013

Language:

english

File:

PDF, 93 KB

english, 2013

35

Sex hormones and breast cancer risk and prognosis

Folkerd, Elizabeth, Dowsett, Mitch

Journal:

Year:

2013

Language:

english

File:

PDF, 266 KB

english, 2013

36

CYP3A Variation, Premenopausal Estrone Levels, and Breast Cancer Risk

Johnson, N., Walker, K., Gibson, L. J., Orr, N., Folkerd, E., Haynes, B., Palles, C., Coupland, B., Schoemaker, M., Jones, M., Broderick, P., Sawyer, E., Kerin, M., Tomlinson, I. P., Zvelebil, M., Chi

Journal:

JNCI Journal of the National Cancer Institute

Year:

2012

Language:

english

File:

PDF, 988 KB

english, 2012

37

Suppression of Plasma Estrogen Levels by Letrozole and Anastrozole Is Related to Body Mass Index in Patients With Breast Cancer

Folkerd, E. J., Dixon, J. M., Renshaw, L., A'Hern, R. P., Dowsett, M.

Journal:

Journal of Clinical Oncology

Year:

2012

Language:

english

File:

PDF, 123 KB

english, 2012

38

Reproducibility of Estradiol and Testosterone Levels in Postmenopausal Women Over 5 Years: Results From the Breakthrough Generations Study

Jones, M. E., Schoemaker, M. J., Rae, M., Folkerd, E. J., Dowsett, M., Ashworth, A., Swerdlow, A. J.

Journal:

American Journal of Epidemiology

Year:

2014

Language:

english

File:

PDF, 159 KB

english, 2014

39

Interpreting Plasma Estrogen Levels in Breast Cancer: Caution Needed

Folkerd, E. J., Lonning, P. E., Dowsett, M.

Journal:

Journal of Clinical Oncology

Year:

2014

Language:

english

File:

PDF, 469 KB

english, 2014

40

Factors influencing estrogen production and metabolism in postmenopausal women with endocrine cancer

V. H. T. James,E. J. Folkerd,R. C. Bonney…

Journal:

Journal of Endocrinological Investigation

Year:

1982

Language:

english

File:

PDF, 1.81 MB

english, 1982

41

Reduced progesterone levels explain the reduced risk of breast cancer in obese premenopausal women: a new hypothesis

Dowsett, Mitch, Folkerd, Elizabeth

Journal:

Breast Cancer Research and Treatment

Year:

2015

Language:

english

File:

PDF, 332 KB

english, 2015

42

Combined effects of endogenous sex hormone levels and mammographic density on postmenopausal breast cancer risk: results from the Breakthrough Generations Study

Schoemaker, M J, Folkerd, E J, Jones, M E, Rae, M, Allen, S, Ashworth, A, Dowsett, M, Swerdlow, A J

Journal:

British Journal of Cancer

Year:

2014

Language:

english

File:

PDF, 194 KB

english, 2014

43

Polymorphisms Associated With Circulating Sex Hormone Levels in Postmenopausal Women

Dunning, A. M., Dowsett, M., Healey, C. S., Tee, L., Luben, R. N., Folkerd, E., Novik, K. L., Kelemen, L., Ogata, S., Pharoah, P. D. P., Easton, D. F., Day, N. E., Ponder, B. A. J.

Journal:

JNCI Journal of the National Cancer Institute

Year:

2004

Language:

english

File:

PDF, 180 KB

english, 2004

44

Selective Inhibition of CYP17 With Abiraterone Acetate Is Highly Active in the Treatment of Castration-Resistant Prostate Cancer

Attard, G., Reid, A. H.M., A'Hern, R., Parker, C., Oommen, N. B., Folkerd, E., Messiou, C., Molife, L. R., Maier, G., Thompson, E., Olmos, D., Sinha, R., Lee, G., Dowsett, M., Kaye, S. B., Dearnaley,

Journal:

Journal of Clinical Oncology

Year:

2009

Language:

english

File:

PDF, 656 KB

english, 2009

45

Influence of Sex Hormones on Cancer Progression

Folkerd, E. J., Dowsett, M.

Journal:

Journal of Clinical Oncology

Year:

2010

Language:

english

File:

PDF, 233 KB

english, 2010

46

Letrozole Suppresses Plasma Estradiol and Estrone Sulphate More Completely Than Anastrozole in Postmenopausal Women With Breast Cancer

Dixon, J. M., Renshaw, L., Young, O., Murray, J., Macaskill, E. J., McHugh, M., Folkerd, E., Cameron, D. A., A'Hern, R. P., Dowsett, M.

Journal:

Journal of Clinical Oncology

Year:

2008

Language:

english

File:

PDF, 162 KB

english, 2008

47

Reply to S. Pauwels et al

Folkerd, E. J., Dixon, J. M., A'Hern, R. P., Dowsett, M.

Journal:

Journal of Clinical Oncology

Year:

2013

Language:

english

File:

PDF, 65 KB

english, 2013

48

Changes in Breast Density and Circulating Estrogens in Postmenopausal Women Receiving Adjuvant Anastrozole

Prowell, T. M., Blackford, A. L., Byrne, C., Khouri, N. F., Dowsett, M., Folkerd, E., Tarpinian, K. S., Powers, P. P., Wright, L. A., Donehower, M. G., Jeter, S. C., Armstrong, D. K., Emens, L. A., Fe

Journal:

Cancer Prevention Research

Year:

2011

Language:

english

File:

PDF, 223 KB

english, 2011

49

RESPONSE: Re: Polymorphisms Associated With Circulating Sex Hormone Levels in Postmenopausal Women

Dunning, A. M., Dowsett, M., Healey, C. S., Luben, R. N., Folkerd, E., Pharoah, P. D. P., Easton, D. F., Bruce, N. E. D., Ponder, A. J.

Journal:

JNCI Journal of the National Cancer Institute

Year:

2005

Language:

english

File:

PDF, 45 KB

english, 2005

50

The Heritability of Mammographic Breast Density and Circulating Sex-Hormone Levels: Two Independent Breast Cancer Risk Factors

Varghese, J. S., Smith, P. L., Folkerd, E., Brown, J., Leyland, J., Audley, T., Warren, R. M. L., Dowsett, M., Easton, D. F., Thompson, D. J.

Journal:

Cancer Epidemiology Biomarkers & Prevention

Year:

2012

Language:

english

File:

PDF, 276 KB

english, 2012

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